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Identification and functional characterization of a p-coumaroyl CoA 2'-hydroxylase involved in the biosynthesis of coumarin skeleton from Peucedanum praeruptorum Dunn. LID - 10.1007/s11103-017-0650-4 [doi]

Yao R AD - Jiangsu Key Laboratory of Bioactive Natural Product Research and State Key Laboratory of Natural Medicines, China Pharmaceutical University, Nanjing, Jiangsu, People's Republic of China. FAU - Zhao, Yucheng Zhao Y AD - Jiangsu Key Laboratory of Bioactive Natural Product Research and State Key Laboratory of Natural Medicines, China Pharmaceutical University, Nanjing, Jiangsu, People's Republic of China. FAU - Liu, Tingting Liu T AD - Jiangsu Key Laboratory of Bioactive Natural Product Research and State Key Laboratory of Natural Medicines, China Pharmaceutical University, Nanjing, Jiangsu, People's Republic of China. FAU - Huang, Chuanlong Huang C AD - Jiangsu Key Laboratory of Bioactive Natural Product Research and State Key Laboratory of Natural Medicines, China Pharmaceutical University, Nanjing, Jiangsu, People's Republic of China. FAU - Xu, Sheng Xu S AD - Institute of Botany, Jiangsu Province and Chinese Academy of Sciences, Nanjing, Jiangsu, People's Republic of China. FAU - Sui, Ziwei Sui Z AD - Jiangsu Key Laboratory of Bioactive Natural Product Research and State Key Laboratory of Natural Medicines, China Pharmaceutical University, Nanjing, Jiangsu, People's Republic of China. FAU - Luo, Jun Luo J AD - Jiangsu Key Laboratory of Bioactive Natural Product Research and State Key Laboratory of Natural Medicines, China Pharmaceutical University, Nanjing, Jiangsu, People's Republic of China. luojun1981ly@163.com. FAU - Kong, Lingyi Kong L AD - Jiangsu Key Laboratory of Bioactive Natural Product Research and State Key Laboratory of Natural Medicines, China Pharmaceutical University, Nanjing, Jiangsu, People's Republic of China. cpu_lykong@126.com.
KEY MESSAGE: A p-coumaroyl CoA 2'-hydroxylase responsible for the formation of ...

Plant Mol Biol. 2017 Aug 18. doi: 10.1007/s11103-017-0650-4. - Full Text - Pubmed

The Proteasome-Interacting Ecm29 Protein Disassembles the 26S Proteasome in Response to Oxidative Stress. LID - jbc.M117.803619 [pii] LID - 10.1074/jbc.M117.803619 [doi]

Wang X AD - University of California, Irvine, United States. FAU - Chemmama, Ilan E Chemmama IE AD - University of California, San Francisco, United States. FAU - Yu, Clinton Yu C AD - University of California, Irvine, United States. FAU - Huszagh, Alexander Huszagh A AD - University of California, Irvine, United States. FAU - Xu, Yue Xu Y AD - National Institutes of Health, United States. FAU - Viner, Rosa Viner R AD - ThermoFisher Scientific, United States. FAU - Block, Sarah Ashley Block SA AD - University of California, Irvine, United States. FAU - Cimermancic, Peter Cimermancic P AD - University of California, San Francisco, United States. FAU - Rychnovsky, Scott D Rychnovsky SD AD - University of California, Irvine, United States. FAU - Ye, Yihong Ye Y AD - National Institutes of Health, United States. FAU - Sali, Andrej Sali A AD - University of California, San Francisco, United States. FAU - Huang, Lan Huang L AD - University of California, Irvine, United States; lanhuang@uci.edu.
Oxidative stress has been implicated in multiple human neurological and other ...

J Biol Chem. 2017 Aug 15. pii: jbc.M117.803619. doi: 10.1074/jbc.M117.803619. - Full Text - Pubmed

Exploring the potential of a structural alphabet-based tool for mining multiple target conformations and target flexibility insight.

Regad L AUID- ORCID: http://orcid.org/0000-0002-9292-5283 AD - Molecules therapeutiques in silico (MTi), INSERM UMR-S973, Paris, France. AD - Universite Paris Diderot, Sorbonne Paris Cite, Paris, France. FAU - Cheron, Jean-Baptiste Cheron JB AD - Molecules therapeutiques in silico (MTi), INSERM UMR-S973, Paris, France. AD - Universite Paris Diderot, Sorbonne Paris Cite, Paris, France. AD - Institut de Chimie de Nice, UMR-CNRS 7272, Faculte des Sciences, Universite de Nice-Sophia Antipolis, Nice, France. FAU - Triki, Dhoha Triki D AD - Molecules therapeutiques in silico (MTi), INSERM UMR-S973, Paris, France. AD - Universite Paris Diderot, Sorbonne Paris Cite, Paris, France. FAU - Senac, Caroline Senac C AD - Molecules therapeutiques in silico (MTi), INSERM UMR-S973, Paris, France. AD - Universite Paris Diderot, Sorbonne Paris Cite, Paris, France. AD - Sorbonne Universites, UPMC Univ Paris 06, CNRS, INSERM, Laboratoire d'Imagerie Biomedicale (LIB), Paris, France. FAU - Flatters, Delphine Flatters D AD - Molecules therapeutiques in silico (MTi), INSERM UMR-S973, Paris, France. AD - Universite Paris Diderot, Sorbonne Paris Cite, Paris, France. FAU - Camproux, Anne-Claude Camproux AC AD - Molecules therapeutiques in silico (MTi), INSERM UMR-S973, Paris, France. AD - Universite Paris Diderot, Sorbonne Paris Cite, Paris, France.
Protein flexibility is often implied in binding with different partners and is ...

PLoS One. 2017 Aug 17;12(8):e0182972. doi: 10.1371/journal.pone.0182972. - Full Text - Pubmed

New insight into the control of peptic ulcer by targeting the histamine H2 receptor. LID - 10.1002/jcb.26361 [doi]

Singh V AD - Department of Microbiology, Synthetic Biology Laboratory, School of Biological Sciences and Biotechnology, Institute of Advanced Research, Koba Institutional Area, Gandhinagar - 382007, India. FAU - Gohil, Nisarg Gohil N AD - Department of Microbiology, Synthetic Biology Laboratory, School of Biological Sciences and Biotechnology, Institute of Advanced Research, Koba Institutional Area, Gandhinagar - 382007, India. FAU - Ramirez-Garcia, Robert Ramirez-Garcia R AD - Department of Microbiology, Synthetic Biology Laboratory, School of Biological Sciences and Biotechnology, Institute of Advanced Research, Koba Institutional Area, Gandhinagar - 382007, India.
Peptic ulcer disease is one of the major challenges in public health globally an ...

J Cell Biochem. 2017 Aug 17. doi: 10.1002/jcb.26361. - Full Text - Pubmed

Impact of phenylalanines outside the dimer interface on phosphotriesterase stability and function. LID - 10.1039/c7mb00196g [doi]

Olsen AJ AD - Department of Chemical and Biomolecular Engineering, New York University, Tandon School of Engineering, New York 11201, USA. FAU - Halvorsen, Leif A Halvorsen LA AD - Center for Genomics and Systems Biology, New York University, New York 10003, USA. FAU - Yang, Ching-Yao Yang CY AUID- ORCID: http://orcid.org/0000-0002-7203-5531 AD - Department of Chemical and Biomolecular Engineering, New York University, Tandon School of Engineering, New York 11201, USA. FAU - Barak Ventura, Roni Barak Ventura R AD - Department of Chemical and Biomolecular Engineering, New York University, Tandon School of Engineering, New York 11201, USA. FAU - Yin, Liming Yin L AD - Department of Chemical and Biomolecular Engineering, New York University, Tandon School of Engineering, New York 11201, USA. FAU - Renfrew, P Douglas Renfrew PD AD - Center for Genomics and Systems Biology, New York University, New York 10003, USA. FAU - Bonneau, Richard Bonneau R AD - Center for Genomics and Systems Biology, New York University, New York 10003, USA and Center for Computational Biology, Flatiron Institute, New York, NY 10010, USA and Courant Institute of Mathematical Sciences, Computer Science Department, New York University, New York, NY 10009, USA. FAU - Montclare, Jin Kim Montclare JK AUID- ORCID: http://orcid.org/0000-0001-6857-3591 AD - Department of Chemical and Biomolecular Engineering, New York University, Tandon School of Engineering, New York 11201, USA and Department of Chemistry, New York University, New York 10003, USA and Department of Biochemistry, SUNY Downstate Medical Center, Brooklyn 11203, USA and Department of Biomaterials, NYU College of Dentistry, New York 10010, USA. montclare@nyu.edu.
We explore the significance of phenylalanine outside of the phosphotriesterase ...

Mol Biosyst. 2017 Aug 17. doi: 10.1039/c7mb00196g. - Full Text - Pubmed