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 Figure 1. Antibody idiotope— the unique set of antigenic determinants of the variable region of an antibody. The idiotype represents the variable part of an antibody, including the unique
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Internalizing antibodies and peptides specific for cell surface receptors, which upon binding will induce receptor-mediated endocytosis, are highly suitable vehicles for targeted delivery of drugs, to
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Epitopes consist of groups of amino acids that lie close together on the protein (antigen) surface and interact with an antibody; they therefore determine antigenicity. Epitopes of proteins are usua
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Humanization is important for reducing the immunogenicity of monoclonal antibodies derived from xenogeneic sources (commonly rodent) and for improving their activation of the human immune system. Sinc
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 Dual Variable Domain Immunoglobulin (DVD-Ig) Production Service provides immunoglobulin molecules that simultaneously target two mediators of disease by a single pharmaceutical entity. With year
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 Many cellular activities are controlled by post-translational modifications, the study of which is hampered by the lack of specific reagents due in large part to their ubiquitous and non-immunog
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 Many cellular activities are controlled by post-translational modifications, the study of which is hampered by the lack of specific reagents due in large part to their ubiquitous and non-immunog
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Starting from a hybridoma cell line: 1. Validation of the hybridoma cell line in terms of antibody production, antibody isotyping and antigen-binding specificity; 2. RNA extraction and reverse tra
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De novo Nanobody Sequencing servicewas developed based on the world-leading platform of de novo antibody sequencing using “Database Assisted Shotgun Sequencing" (DASS) technology. Solu
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With the consistent growth of therapeutic antibodies in global market, many efforts have been made to improve the engineering technologies, safety and efficacy of therapeutic antibodies, among which
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