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Safety, pharmacokinetics of 3 morpholino oligos for treatment of DMD

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Status: Frog Laureate
Frog Laureate
Topic Started by jonmoulton
on 12/23/2015 16:13 PM   
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Sazani P, Magee T, Charleston JS, Shanks C, Zhang J, Carver M, Rodino-Klapac L, Sahenk Z, Roush K, Bird L, Lowes LP, Alfano L, Gomez AM, Lewis S, Malik V, Shontz K, Flanigan K, Shilling C, Bhalli J, Kaur H, Walisser J, Forget J, Saoud J, Mendell JR, Kaye E.  Safety and pharmacokinetic profile of eteplirsen, SRP-4045, and SRP-4053, three phosphorodiamidate morpholino oligomers (PMOs) for the treatment of patients with Duchenne muscular dystrophy (DMD). Neuromusc Dis. 2014. 24(9-10):828. doi:10.1016/j.nmd.2014.06.124

Jon D. Moulton, Ph.D. Gene Tools, LLC

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